Pin1 mutant
WebJan 22, 2002 · A comparison of body weight of 10 wild-type and Pin1 −/− mutant male and female mice at ≈3.5 and ≈7 months is shown in B. (C and D) Testicular atrophy, as indicated by representative testis from wild-type or Pin1 −/− mouse at ≈3.5 months old (C) or by histopathological comparison (D). Testicular sections obtained from ≈3.5- and ... WebAug 2, 2024 · PIN1 adopts a NhaA fold; this fold was first observed in the bacterial Na + /H + antiporter 27 and is shared by mammalian Na + /H + exchangers 28 and apical sodium-dependent bile acid transporter...
Pin1 mutant
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WebMay 26, 2005 · Clearly, pin1-1 is a key developmental mutant, and data on its endogenous IAA levels are critical. Surprisingly, such data are rare, especially for individual plant parts. The results of Reinhardt et al. imply … WebPin1 is phosphorylated at S138 by mixed-lineage kinase 3 (MLK3) (Figure 1B) . The phosphorylation of S138 increases isomerase activity . The phosphorylation mimicking …
Webp53 protein is a well-known tumor suppressor factor that regulates cellular homeostasis. As it has several and key functions exerted, p53 is known as “the guardian of the genome” and either loss of function or gain of function mutations in the TP53 coding protein sequence are involved in cancer onset and progression. The Hippo pathway is a key regulator of … WebOur results suggest that PIN1 plays a role in cancer cell proliferation, migration and invasion in a different manner according to the TP53 gene mutation status in HCC. In particular, interaction of PIN1 with mutant TP53 can act as a tumor promoter and increase its oncogenic activities in HCC. MeSH terms Adult
The gene encoding Pin1 was identified in 1996 as a result of a genetic/biochemical screen for proteins involved in mitotic regulation. It was found to be essential for cell division in some organisms. By 1999, however, it was apparent that Pin1 knockout mice had a surprisingly mild phenotype, indicating that the enzyme was not required for cell division per se. Further studies later found that loss of Pin1 in mice displays are not only neuronal degenerative phenotypes but … WebNov 4, 2013 · The agb1-2 single mutant also displayed increased basipetal auxin transport comparable to plants with downregulated NDL (Fig. 7A), which corresponds with the phenotypic data. Plants lacking AGB1 or with a sub-optimal level of NDL showed abnormally high auxin transport capacity. ... Polar auxin transport in shoots requires basally localized …
WebJan 1, 2011 · The Arabidopsis pin1 mutant wa s fully rescued by the SLM1 CDS driven by the. Arabidopsis PIN1 promoter. The Arabidopsis mutant and complemented plants (A), flowers (B) and leaves (C) are shown.
jane healy books in orderWebAug 17, 2007 · (A) The triple mutant yuc1 yuc4 pin1 did not make a leaf. Seedlings shown are 7 d old and grown on 0.5× Murashige and Skoog media. Arrow points to the apex of yuc1 yuc4 pin1. The pin1 mutant was a null mutant caused by a T-DNA insertion. lowest new car loan rateWebMar 25, 2015 · To investigate the differential response of pin1 and pin2 mutants under low-B conditions, the effect of low-B on PIN1–green fluorescent protein (GFP) and PIN2–GFP … lowest new car loanWebNational Center for Biotechnology Information jane hay the real estate groupWebAug 26, 2024 · The first PIN to be cloned was PIN1 from Arabidopsis thaliana. The pin1 mutant exhibited defective inflorescence development, lacked cauline leaves and floral organs, and had a pin-head trait . Subsequently, seven more … jane healy md phdWebJun 17, 2013 · PIN1 down-regulation and pin1-5 mutation severely affect female gametophyte development since embryo sacs arrest at the mono- and/or bi-nuclear stages (FG1 and FG3 stage). PIN3 function is not required for ovule development in wild-type or PIN1 -silenced plants. jane headington carleton collegeWebOct 13, 2024 · Abstract. The oncogenic transcription condition B-Myb is an essential regulator of slow cellphone cycle dna whose activation by phosphorylation is still poorly unders lowest new car loan interest rates