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Plicamine-type alkaloids

WebbTotal synthesis of the plicamine‐type alkaloids zephycarinatines C and D has been achieved. The key feature of the synthesis is a stereoselective radical ipso‐cyclization using visible‐light‐mediated photoredox catalysis. WebbSeven undescribed Amaryllidaceae alkaloids classified into four types, including the plicamine-type, secoplicamine-type, belladine-type and pretazettine-type, along with …

Acetylcholinesterase Inhibitory Alkaloids from the Whole Plants of ...

Webb27 jan. 2024 · All the alkaloids were in vitro evaluated for their cytotoxic activities against six glioma cell lines (CHG - 5, SH-SY5Y, SHG - 44, U251, U343, and GL15). Alkaloids 2 and 3 exhibited significant cytotoxic activities against all tested cell lines with IC 50 values of less than 20 μM. KEYWORDS: Webb13 okt. 2024 · Pyrrolizidine alkaloids (PAs) with 1,2-unsaturated necine base are hepatotoxic phytotoxins. Acute PA intoxication is initiated by the formation of adducts between PA-derived reactive pyrrolic metabolites with cellular proteins. The present study aimed to investigate the correlation between the formation of hepatic pyrrole–protein … aliona origine https://roschi.net

Cytotoxic and anti-inflammatory active plicamine alkaloids from ...

Webb17 juni 2002 · Total synthesis of the amaryllidaceae alkaloid (+)-plicamine and its unnatural enantiomer by using solid-supported reagents and scavengers in a multistep … WebbPhotocycloaddition and Rearrangement Reactions in a Putative Route to the Skeleton of Plicamine-Type Alkaloids Karl-Heinz Rimböck Department Chemie and Catalysis … Webb4 apr. 2024 · The Amaryllidaceae species are well-known as a rich source of bioactive compounds in nature. Although Hymenocallis littoralis has been studied for decades, its polar components were rarely explored. The current phytochemical investigation of Amaryllidaceae alkaloids from H. littoralis led to the identification of three previously … aliona romanova

Antiproliferative Amaryllidaceae alkaloids from the bulbs of ...

Category:Proceedings Free Full-Text Amaryllidaceae Alkaloids from ...

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Plicamine-type alkaloids

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WebbPhytochemical investigation on the 80% EtOH extract of the whole plants of Zephyranthes grandiflora afforded three new 4a-epi-plicamine-type alkaloids, zephyranthines A-C (1-3). Structural elucidation of all the compounds were performed by spectral methods such as 1D and 2D (¹H- ¹H COSY, HMQC, and HMBC) NMR spectroscopy, in addition to high … Webb1 maj 2024 · Isocarbostyril alkaloids is a kind of alkaloid does not contain basic nitrogen atoms and is represented by hydroxylated benzophenanthridone or isoquinolinone types …

Plicamine-type alkaloids

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Webb1 jan. 2024 · Plicamine-type alkaloids have been found in the phylogenetically unrelated genera Galanthus, Narcissus, Cyrtanthus and Zephyranthes. 53, 207, 213, 215, 226. … Webb1 sep. 2024 · As a result, alkaloids 1-3 exhibited some cytotoxic activity against all the tested tumor cell lines with IC 50 values <20 μM and 1 and 2 displayed anti-inflammatory …

Webb1 okt. 2024 · The results showed plicamine-type alkaloids 1 and 2 with ketone of C-6 exhibited more potent cytotoxicity (IC 50 values from 9.2 to 10.6 and from 12.4 to 13.9 … Webb28 apr. 2013 · Ghosal et al. recognised 12 distinct ring types when reviewing the alkaloids of the genus Crinum , a classification also followed by Evidente and Kornienko . Unver introduced two new subgroups called the graciline-type and the plicamine-type, the latter containing two nitrogen atoms .

WebbPhytochemical investigation on the 80% EtOH extract of the whole plants of Zephyranthes grandiflora afforded three new 4a-epi-plicamine-type alkaloids, zephyranthines A-C (1-3).Structural elucidation of all the compounds were performed by spectral methods such as 1D and 2D (1 H-1 H COSY, HMQC, and HMBC) NMR spectroscopy, in addition to high … WebbThe minor alkaloids, (+)-plicamine (I) and (-)-secoplicamine (II), from Galanthus plicatus subsp. byzantinus are the first examples of dinitrogenous alkaloids where the oxygen atom in position 7 of the basic tazettine mol. has been replaced by a nitrogen atom substituted by a pendant 4-hydroxyphenethyl moiety. O O N NMe OH H H O O N O N OH H ...

Webb1 maj 2024 · Seven undescribed Amaryllidaceae alkaloids classified into four types, including the plicamine-type, secoplicamine-type, belladine-type and pretazettine-type, along with another three alkaloids that have not been isolated from plant material and seven known alkaloids, were isolated from the bulbs of Hymenocallis littoralis (Jacq.) …

Webb12 sep. 2024 · Eleven new alkaloids (1–11), classified as the 12-acetylplicamine (1), N-deformyl-seco-plicamine (2), plicamine (3–6), 4a-epi-plicamine (7), seco-plicamine (8), … aliona rudaiaWebb12 juni 2002 · Total synthesis of the plicamine‐type alkaloids, zephycarinatines C and D has been achieved. The key feature of the synthesis is a stereoselective radical … a lion among menaliona muratovWebbAmaryllidaceae alkaloids have been isolated in more than 40 wild species and over 100 cultivars. The most common alkaloids in Narcissus species are lycorine- and homolycorine-types; notably, they do not contain crinine-type alkaloids, as they synthesise alkaloids with the 5,10b-ethano bridge in an α, not β position [8]. aliona raduWebb1 juni 1974 · Amaryllidaceae alkaloids with new framework types from Zephyranthes candida as potent acetylcholinesterase inhibitors European Journal of Medicinal Chemistry, Volume 127, 2024, pp. 771-780 Show abstract Research article aliona rusuWebbT. GOEZLER's 6 research works with 60 citations and 249 reads, including: ChemInform Abstract: The Gracilines: A Novel Subgroup of the Amaryllidaceae Alkaloids ali onariWebbAll the alkaloids were in vitro evaluated for their cytotoxic activities against six glioma cell lines (CHG-5, SH-SY5Y, SHG-44, U251, U343, and GL15). Alkaloids 2 and 3 exhibited … aliona scerbatiuc