WebbTotal synthesis of the plicamine‐type alkaloids zephycarinatines C and D has been achieved. The key feature of the synthesis is a stereoselective radical ipso‐cyclization using visible‐light‐mediated photoredox catalysis. WebbSeven undescribed Amaryllidaceae alkaloids classified into four types, including the plicamine-type, secoplicamine-type, belladine-type and pretazettine-type, along with …
Acetylcholinesterase Inhibitory Alkaloids from the Whole Plants of ...
Webb27 jan. 2024 · All the alkaloids were in vitro evaluated for their cytotoxic activities against six glioma cell lines (CHG - 5, SH-SY5Y, SHG - 44, U251, U343, and GL15). Alkaloids 2 and 3 exhibited significant cytotoxic activities against all tested cell lines with IC 50 values of less than 20 μM. KEYWORDS: Webb13 okt. 2024 · Pyrrolizidine alkaloids (PAs) with 1,2-unsaturated necine base are hepatotoxic phytotoxins. Acute PA intoxication is initiated by the formation of adducts between PA-derived reactive pyrrolic metabolites with cellular proteins. The present study aimed to investigate the correlation between the formation of hepatic pyrrole–protein … aliona origine
Cytotoxic and anti-inflammatory active plicamine alkaloids from ...
Webb17 juni 2002 · Total synthesis of the amaryllidaceae alkaloid (+)-plicamine and its unnatural enantiomer by using solid-supported reagents and scavengers in a multistep … WebbPhotocycloaddition and Rearrangement Reactions in a Putative Route to the Skeleton of Plicamine-Type Alkaloids Karl-Heinz Rimböck Department Chemie and Catalysis … Webb4 apr. 2024 · The Amaryllidaceae species are well-known as a rich source of bioactive compounds in nature. Although Hymenocallis littoralis has been studied for decades, its polar components were rarely explored. The current phytochemical investigation of Amaryllidaceae alkaloids from H. littoralis led to the identification of three previously … aliona romanova