WebbThe applicant will combine cell and molecular biology state-of-the-art techniques such as ChIP-seq, RNA-seq, single-cell RNA-seq, ATAC-seq, CLIP-seq and other epigenomic and epitranscriptomic analyzes. Embryonic stem cells, and several differentiation models will be used to study how epigenetic and epitranscriptomic marks regulate pluripotency. Webbp-value: 1e-1710: log p-value:-3.939e+03: FDR: NA: Information Content per bp: 1.783: Number of Target Sequences with motif: 5118.0: Percentage of Target Sequences with motif
Some Basic Analysis of ChIP-Seq Data - bioconductor.org
Webb1 jan. 2024 · TEADi TEAD inhibitor Introduction The Hippo pathway is one of the main signaling networks altered in human cancer ( Sanchez-Vega et al., 2024 ), with genomic and signaling changes in Hippo components leading to activation and nuclear translocation of YAP1 and TAZ ( WWTR1). WebbChromatin immunoprecipitation followed by sequencing (ChIP-seq) is a technique for genome-wide profiling of DNA-binding proteins, histone modifications or nucleosomes. Owing to the tremendous progress in next-generation sequencing technology, ChIP-seq offers higher resolution, less noise and greater coverage than its array-based … bootsbootsboots.ca
AmelHap: Leveraging drone whole-genome sequence data to …
Webb21 aug. 2015 · To identify YAP1 binding sites genome-wide we performed chromatin immunoprecipitation with a YAP1-specific antibody followed by high-throughput … Webb31 jan. 2024 · AIB1 and TEAD ChIP-seq: Organism: Homo sapiens: Experiment type: Genome binding/occupancy profiling by high throughput sequencing: Summary: We report the global occupancy by ChIP-seq of AIB1 and TEAD4 in normal mammary epithelial cells (MCF10A). We performed ChIP and library preparation with the ActiveMotif Low Cell … Webb8 feb. 2024 · ChIP-seq of Tead1 and Tead4 identified their binding sites C2C12 cells and in mature muscle fibres. RNA-seq identified distinct but overlapping sets of genes … hater sauce